You are viewing the site in preview mode

Skip to main content

Table 1 Clinical and tumor characteristics

From: Cell-free DNA and circulating TERT promoter mutation for disease monitoring in newly-diagnosed glioblastoma

Characteristics Number of patients (%)
Age (years), mean ± SD 58.3 ± 9.5
Sex
 Female 22 (42.3%)
 Male 30 (57.7%)
Surgery
 Biopsy 20 (38.4%)
 Resection 32 (61.6%)
Karnofsky performance score
 ≥ 80% 45 (86.5%)
 ≥ 70 to < 80% 6 (11.5%)
 < 70% 1 (2%)
Tumor Characteristics
Volume at baseline, mean ± SD
 T1-weighted with Gadolinium W/necrosis 31.1 cm3 ± 28.6
 T1-weighted with Gadolinium W/O necrosis 18 cm3 ± 16.5
 Necrosis part, mean (%) 33% [min. 0–max. 87%]
 Flair 114.9 cm3 ± 63.2
Histology
 Glioblastoma-IDH wild type 46 (88.4%)
 Glioblastoma IDH-mutated 3 (5.8%)
 Gliosarcoma 3 (5.8%)
MGMTp methylation
 Non-methylated 26 (50%)
 Low methylation profile 2 (4%)
 Methylated 12 (23%)
 Unknown 12 (23%)
TERTp mutation
 C228T 44 (84.6%)
 C250T 1 (1.9%)
 Wild-type (wt) 6 (11.6%)
 Unknown 1 (1.9%)