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Characteristics
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Number of patients (%)
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|---|
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Age (years), mean ± SD
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58.3 ± 9.5
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Sex
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Female
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22 (42.3%)
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Male
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30 (57.7%)
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Surgery
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Biopsy
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20 (38.4%)
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Resection
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32 (61.6%)
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Karnofsky performance score
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≥ 80%
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45 (86.5%)
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≥ 70 to < 80%
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6 (11.5%)
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< 70%
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1 (2%)
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Tumor Characteristics
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Volume at baseline, mean ± SD
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T1-weighted with Gadolinium W/necrosis
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31.1 cm3 ± 28.6
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T1-weighted with Gadolinium W/O necrosis
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18 cm3 ± 16.5
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Necrosis part, mean (%)
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33% [min. 0–max. 87%]
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Flair
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114.9 cm3 ± 63.2
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Histology
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Glioblastoma-IDH wild type
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46 (88.4%)
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Glioblastoma IDH-mutated
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3 (5.8%)
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Gliosarcoma
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3 (5.8%)
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MGMTp methylation
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Non-methylated
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26 (50%)
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Low methylation profile
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2 (4%)
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Methylated
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12 (23%)
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Unknown
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12 (23%)
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TERTp mutation
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C228T
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44 (84.6%)
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C250T
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1 (1.9%)
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Wild-type (wt)
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6 (11.6%)
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Unknown
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1 (1.9%)
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