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Table 2 Clinical characteristics of the 80 patients with pneumococcal meningitis and 69 controls in the follow up study

From: Individual responsiveness of macrophage migration inhibitory factor predicts long-term cognitive impairment after bacterial meningitis

Characteristics Patients (n = 80)
n/N (%)
Controls (n = 69)
n/N (%)
Male 39/80 (49%) 35/69 (51%)
Age in years* 63 (56–69) 65 (54–68)
Predisposing conditions before admission
 Duration of symptoms < 24 h
 Sinusitis/otitis media
 Pneumonia
 Immunocompromised state
35/79 (44%)
44/79 (55%)
10/78 (13%)
16/80 (20%)
 
Clinical characteristics on admission
 Classic triad
 Coma
 Focal neurologic deficits
35/76 (44%)
4/80 (5%)
18/79 (23%)
 
Laboratory characteristics on admission*
 Blood leukocyte count (× 10^9 cells/L)
 CSF leukocyte count (× 10^6 cells/L)
17.5 (13.3–23.6)
3492 (1298–7805)
 
Standard dose of dexamethasone therapy 69/80 (86%)  
Clinical course/complications
 Seizures
 Circulatory shock
 Intensive care admission
 Cerebral infarction
12/76 (15%)
1/73 (1%)
26/77 (33%)
7/69 (9%)
 
Outcome at discharge
 GOS 3
 GOS 4
 GOS 5
2/80 (3%)
17/80 (21%)
61/80 (76%)
 
Years from discharge to testing* 2.5 (1.1—4.6)  
  1. *Median (IQR 25–75)